In the 7 October issue, the journal Science is launching NextGen VOICES, a new feature that calls upon young scientists to speak up. Make your ideas known! A selection of the best responses will be published in the 6 January 2012 issue of Science. Science will ask a question and collect brief essays, the best of which will be published in a future issue. Here is the question: How will the practice of science change in your lifetime? What will improve and what new challenges will emerge? (Please respond in 250 words or less.). To submit, go to: http://scim.ag/NextGen1br The submission deadline is 18 November.